Category: Medicine


Identifying the genetic basis of cystic fibrosis Cystic fibrosis CF is a genetic disorder long known to be inherited as an autosomal recessive character, and to be highly variable in its severity, duration, and spectrum of symptoms. This cell line is covered by a U of M patent, so if the CFF funded this type of research without sub-licensing rights, the funded company would have to apply for a license with the U of M to do their research. Check it out https: David is concerned that his wife is going to leave him. The Hopkins patent expired in April

The patents did not therefore produce a single-source testing service, the business model adopted by Athena Diagnostics, Myriad Genetics, and others that has been accompanied by intense controversy see case studies on genetic testing for long-QT and other cardiac channelopathies 1 , breast and ovarian vs. Not much was known about whether a potential protein-based therapeutic could be developed, since the function of the CFTR gene was not yet known, other than hints it was an ion channel for chloride. Which instruction should the Nurse Educator include when discussing respiratory complications? In spite of the rush to file the patent application, considerable thought and attention were devoted to constructing an appropriate licensing strategy to allow use of the CFTR gene sequence in various applications, including carrier screening, diagnostics, therapeutics, and research. He did this to avoid a conflict of interest in making decisions, and to avoid being dragged into the many controversies over gene patenting and licensing and also, of course, to support the charity —in addition to supporting further CF research.

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Pediatric Cystic Fibrosis Case Study

The optimal test approach might depend in part on mutational complexity that was not known when the patent application was filed. The U of M developed two license sudy for diagnostic purposes, one for hospitals, clinics, and diagnostic companies for in-house genetic testing, and the other for companies to manufacture and sell diagnostic kits.

Administering digestive enzymes before meals as prescribed 2. The precise molecular definition of CF led to genetic subtyping; to earlier and much more precise diagnosis, and thus improved medical management; and to the first genotype-specific treatment. Perform chest percussion and postural drainage 2 times a day.

Furthermore, if a patient advocacy organization lacks the monetary resources required to fully fund the initial stages of therapeutic research and to cover the cost of sub-licensing, then this licensing strategy might not be as successful as it has been for the CFTR patents. Which intervention should the nurse implement first?

Since the licensing of these patents has not impeded clinical access to genetic testing, we sought to understand how this successful licensing model was developed and whether it might be applicable to other gene patents.

The clause was incorporated into every license the U of M has issued since. Impact of gene patents and licensing practices on access to genetic testing for inherited susceptibility to cancer: In Januarythe Food and Drug Administration approved ivacaftor to treat the roughly four percent of CF patients with the p. Cook-Deegan R, Heaney C. Considerations for therapeutics were entirely different.

It distinguished the CF licensing process from patenting and licensing of Canavan Disease 4 and BRCA 5 patents for genetic testing, where patent-related controversy dogged the history of genetic diagnostics.

hesi cystic fibrosis case study

Which instruction should the Nurse Educator include when discussing respiratory complications? Nuffield Council on Bioethics: Check it out https: Instead, because the U of M gave the CFF the right to sub-license, companies only need to deal with the CFF, thereby reducing the amount of time they have to deal with obtaining a license from the U of M and expediting their research by a few months.

hesi cystic fibrosis case study

This story has a successful ending, but it also shows how the complex patent landscape could have thwarted its development, because the final treatment necessarily involves several patented technologies. Cystic fibrosis CF is a genetic disorder long known to be inherited as an autosomal recessive character, and to be highly variable in its severity, duration, and spectrum of symptoms.

Licensing cyztic CFTR patents was also a tool for managing the quality of genetic testing on at least one occasion 2. The search for the genetic underpinning of CF began in the s with unsuccessful attempts to identify linkage with known blood groups 16 Although this particular licensing strategy is currently only used by the U of M with respect to the CFTR patent, Ritchie does draw from it to help draft other licensing agreements with other entities:.

It enabled continuing research, wide-spread CF diagnostic testing and newborn and carrier stydy, and facilitated development of CF therapeutics.

HESI Case Studies-Pediatrics-Cystic Fibrosis (Debbie Baker) –

The inclusion and active participation of the CFF patient advocacy organization was another important factor in the initial patenting and licensing discussions. We have a quiet room you can use that is private and close by. David is concerned that his wife is going to leave him. There were 18—20 active licenses at the time of our interview. DiSante was flooded with phone calls from companies interested in securing an exclusive license from the U of M. Guideline for the Licensing of Genetic Inventions.

An early diagnosis is the first step in effectively managing the disease, and genetic testing has been used in carrier screening, prenatal genetic testing, and diagnosis.

Assess Debbie and the child that received the wrong medication.

If the technologies were successful, then the university would benefit in other areas, sstudy advancing and enhancing its reputation and providing a royalty stream to support education and research. The child will be able to remove mucus from the airway by coughing. Part of the variability in CF is due to a large number of genetic mutations that have variable effects on CFTR protein function.


Moira Gutteridge – – Informal Logic 9 2. History of Western Philosophy. Critical Thinking Across the Disciplines 28 1: Making Critical Thinking Visible. The California critical thinking skills test:

In this sub-module on the APA Delphi report by experts on critical thinking, participants will: Electronics, Computer Networking Learning goal: Amanda Hiner – – Inquiry: Critical Thinking Across the Curriculum: Critical Thinking in the Schools: The Disposition Toward Critical Thinking:

My profile My library Metrics Alerts. Expert consensus statement regarding critical thinking and the ideal critical thinker: Request removal from index. Design a Facione based activity example from one’s area of choice or expertise, clearly showing how it can be used for improving learning.

In the American Philosophical Association conducted as Delphi research study for determining core critical thinking based on the consensus of experts within the US and Canada, representing disciplines in the humanities, sciences, social sciences and education.

Facione – – Informal Logic 20 1: Research Findings and Recommendations. California Academic Press The experts revise their answers based on the replies from the panel.

The system can’t perform the operation now. Reflections on Critical Thinking: Crigical Thinking Across the Disciplines 21 1: Ennis – – Inquiry: Experimental Validation and Content Validity.

Responses to prompts are usually brief and do not directly address qualities associated with critical thinking. Did I show tolerance toward the beliefs, ideas, or opinions of someone with who I disagreed: Thinking Critically About Critical Thinking.

Hhinking critical thinking disposition inventory: Paul-Elder’s Model of Critical Thinking.

The Journal of General Education 50 1, Position mouse no need to click over the top portion of the black colored box below to reveal the correct quiz answers under it.

The six core critical fzcione skills according to the experts are: Example of practice in one’s discipline. Critical Thinking Across the Disciplines 28 3: New articles related to this author’s research. Bloom’s Taxonomy of Learning Objectives.

Peter Facione – Google Scholar Citations

Facioe statement of expert consensus for purposes of educational assessment and instruction The Delphi Report P Facione. Their combined citations are counted only for the first article.

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This is the full version of the Delphi Report on critical thinking and critical thinking instruction at the post-secondary level. Provide the modified way in which the topic is to be covered and, optionally, how it improves learning.

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This process reasoned consideration to evidence, context, conceptualizations, methods, and criteria. Why Doesn’t Much Happen?

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The zoo does not have an advertising budget. The animals, birds, and reptiles look well cared for. Would simple linear regression analysis be the appropriate forecasting technique? This case serves to illustrate how a nonprofit institution can respond to technological, economic, and social changes. In response, the Akron Zoological Park was organized as a corporation to operate the zoo under contract with the city.

Faced with uncertain prospects, the city of Akron opted out of the zoo business. They are a strong reason that annual zoo attendance has increased. For example, attendance was down during the month of December , which established many local records for the coldest temperature and the most snow. The Clear Answers and Start Over feature requires scripting to function. In response, the Akron Zoological Park was organized as a corporation to contract with the city to operate the zoo. The animals, birds, and reptiles look well cared for. It reopens for one week at Halloween and for the month of December.

Managerial Decision Analysis Case study – Akron Zoological Park

Chapter 2 Akron Besides the admission price, what other factors that influence annual attendance should be considered in the forecast?

Children accounted for one-half of the paid attendance. To gain exposure in its market, then, the zoo depends on public service announcements, the zoo’s public television series, and local press coverage of its activities and social happenings. Akroj Submit Answers for Grading feature requires scripting to function.

Although the Akron Stuey Park made it through recent turbulent and difficult times, to keep the zoo open and financially solvent, the CEO believes she needs to develop new programs and add new facilities to the institution. Variations in weather also affect crop yields and prices of fresh animal foods, thereby influencing the costs of animal maintenance.

Its animal exhibits are clean and neat. Paark Study from University of San Francisco: It reopens for one week at Halloween and for the month of December. Besides admission price, what other factors that influence annual attendance should be considered in the forecast? The Demand for Zoos and Aquariums.

The President of the Akron Zoo asked you to calculate the expected gate admittance figures and revenues for both and Children account for one half of the paid attendance. They are a strong reason that annual zoo attendance zoolgical increased.

Many of these activities are but a few years old.

The Akron Zoological Park

Would simple linear-regression analysis be the appropriate forecasting technique? Click here to sign up. Would simple linear regression analysis be the appropriate forecasting technique?

As resources become available for construction and continuing operations, the zoo also keeps adding new sthdy and activities. Many of these activities are only a few years old and are a strong reason why attendance has increased. Help Center Find new research papers in: In response, the Akron Zoological park was organized as a corporation pari contract with the city to operate the zoo.

case study akron zoological park

Yet, she must balance the costs of this approach with the flows of operating revenues. The president of the Akron Zoo has asked you to calculate the expected gate admittance figures and revenues for both and The zoo does not have an advertising budget.

The following Clear Answers button is provided in sutdy place and will clear your answers: As resources become available for construction and continuing operations, the zoo keeps adding new exhibits and activities.

Due to its northern climate, the zoo conducts its open season from mid-April until mid-October. Enter the email address you signed up with and we’ll email you cawe reset link.

Akron Zoological Park

Lagging attendance and a low level of memberships did not help matters. Faced with uncertain prospects of continuing, the city of Akron opted sthdy of the zoo business. But the zoo became known as an innovative community resource, and as indicated in the table below, annual paid attendance doubled.

case study akron zoological park

Group admissions remain a constant 15 percent of zoo attendance. Log In Sign Up. The Demand for Zoos and Aquariums.


He saved my ass with some statistics magic, by utilizing a different analysis procedure that obtained significant results. And we had to collect a total of participants which was thankfully later reduced — although I still have to collect till now for publishing. Let’s first look at time which you can precisely pinpoint. Ideally, he should be somewhere in between. November Send the necessary stuff e. Other stuff CCA, leadership, volunteering etc.

This was a very daunting and difficult first step into thesis. Each draft took maybe a week at most to read – a really quick turnaround. Also, taking it early would give you some time to retake it if your scores are not good enough. One way to do this is to combine all these little reimbursements from all your offers such that you have enough for a single trip, then do all your interviews during that single trip. Thus I hope this entry will help people to make a more informed decision.

A strong statement will get you noticed by the admissions committee. Experience can come from labs that are not relevant, content-wise, to your field. What are the requirements for graduate school?

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And we had to collect a total of participants which was thankfully later reduced — although I still have to collect till now for publishing My introverted nature and inhibitions to speak to and bother strangers had to be totally discarded away, and I had to be the total opposite of what I usually was — convincing, persuasive and bright.

Take some programming modules in school so you have something tangible to put on your CV. Contact me if you need any advice!

Intro 17 pgs, Methods 5 pgs, Results 9 pgs, Discussion 8 pgs. I was generally fine with most topics, and I asked quite late after my exchange finished about 6 months beforeso I kind of emailed profs down the list in the NUS Psych webpagetweaking my email to suit each prof.

honours thesis psychology nus

October Ask your professors for LORs. You would need to already have a specific topic in mind, and some schools most notably Oxbridge require you to submit a research proposal at the time of application. How do I approach him? Good grades high second-upper or first class. How long was the different part of your thesis?

Nus Honours Thesis Psychology

Psychologh you are unsure if you want to do academia, do a Masters research first. UK programmes are really just researching all the way. If you would like to find out more or apply, drop us an email at nuschildlab nus.

For your thesis, you typically run one experiment it really depends on subject matter – for instance, Health Psychology topics may involve going to pychology to interview patients or somethingand assuming about participants, and the worst case scenario of 1 ppt at a time, that’s about 90 hours I ran about 10 participants at a time, so it was about 9 hours? The best-case scenario is thus if all 3 letters come from professors you have done research within the past e.

Yr 3 Sem 2: Go through the abstracts of recent conferences to see which professors are currently doing research that interests you. I think many profs would have some research questions in mind but no time to do it themselves. Also, you can take more higher-level or even graduate-level courses to show that you can handle challenging material.

NUS Module Review: Yr 4 Sem 2 (2016/17)

Do you want to be a cool kid in LA? I ns approached mine once in Y2S2, and once at the end of Y3S1 when he accepted me. Newer Post Older Post Home. You can email your POI to ask about your application, and what can be improved.

NUS Module Review: PL Honours Thesis & PLG Positive Psych

Takes 2 years usually. How much reading do you have to do?

honours thesis psychology nus

Check the following websites for PhD studentship openings:. One of the schools I applied to also told me that it would be easier to get in if I have my own source of funding.

Hi there, thanks for the questions! Something about watching the timer counting down my time makes me take action lolol. I would say 3 different labs would be the best since you would need 3 LORs.

Honours Thesis – Faculty of Arts and Social Sciences – NUS where students develop their own research questions, conduct independent fieldwork and analyse their data under close guidance from their supervisors. See also the previous section on contacting professors.


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Decompose non-unit fractions and represent them as a whole number times a unit fraction using tape diagrams. Use place value understanding to decompose to smaller units once using the standard subtraction algorithm, and apply the algorithm to solve word problems using tape diagrams. Recognize a digit represents 10 times the value of what it represents in the place to its right. Year in Review Days: Identify, define, and draw parallel lines. Multi-digit multiplication and division Topic H:

Solve word problems with line plots. Use place value understanding to round multi-digit numbers to any place value using real world applications. Practice and solidify Grade 4 fluency. Application of metric unit conversions: Extend the use of place value disks to represent three- and four-digit by one-digit multiplication. Name numbers within 1 million by building understanding of the place value chart and placement of commas for naming base thousand units. Video Video Lesson

Express metric capacity measurements in terms of a smaller unit; model and solve addition and subtraction word problems involving metric capacity. Model mixed numbers with units of hundreds, tens, ones, tenths, and hundredths in expanded form and on the place value chart.

Fraction addition and subtraction: Add a mixed number and a fraction. Two-Dimensional Figures and Symmetry Standard: The Lesson Plans and Worksheets are divided into seven modules. Compare fractions greater than 1 by reasoning using benchmark fractions.

4th grade (Eureka Math/EngageNY)

Interpret and represent patterns when multiplying by 10,and 1, in arrays and numerically. Repeated Addition of Fractions as Multiplication Standard: Use visual models to add and subtract two fractions with the same units. Interpret and find whole number quotients and remainders to solve one-step division word problems with larger divisors of 6, 7, 8, and 9.

Parallel and perpendicular lines review Topic A: Problem solving with the addition of angle measures: Name numbers within 1 million by building understanding of the place value chart and placement of commas for naming base thousand units. Recognize a digit represents 10 times the value of what it represents in the place to its right. Lines and Angles Standard: Application of metric unit conversions: Sketch given angle measures and verify with a protractor.

Homework Help / Module 3

Solve multi-step word problems using the standard addition algorithm modeled with tape diagrams and assess the reasonableness of answers using rounding. Exploring a fraction pattern: Draw right, obtuse, and acute angles.

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Multiply two-digit multiples of 10 by two-digit multiples of 10 with the area model. Use visual models to add and subtract two fractions with the same units, including subtracting from one whole.

Find whole number quotients and remainders. Explain fraction equivalence using a tape diagram and the number line, and relate that to the use of multiplication and division. Money Amounts as Decimal Numbers Standard: Determine whether a whole number is a multiple of another number. Compare fractions greater than 1 by creating common numerators or denominators. Create and determine the area of composite figures. Some of the resources may state they are from EngageNY modules.

Compare and order mixed numbers in various forms. Solve problem involving mixed units of time.

eureka math lesson 2 homework 4.3

There may be videos or videos added later to these resources to help explain the homework lessons. Fraction equivalence, ordering, and operations Topic C: Decompose fractions using area models to show equivalence. Addition and subtraction of fractions by decomposition:


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Dissertation therapeutisches reiten

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Z-dependent cellular responses to a persistent DNA double-strand break.

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